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It is not medical advice, is not a dosing instruction, and does not replace your prescriber or pharmacist
Conditions to note include Type 2 diabetes or prediabetes, hypertension, high cholesterol or triglycerides, sleep apnea, PCOS, fatty liver disease, osteoarthritis (especially in weight-bearing joints), GERD, and cardiovascular disease
Additionally, studies in rats have shown an elevated risk of medullary thyroid carcinoma in rodents exposed to the peptide
This is why the STEP trial protocol includes two intermediate doses (1.7 mg) before reaching 2.4 mg, and why many people find their sweet spot below maximum
Semaglutide injections typically reach peak blood levels within 13 days, while oral tablets take longer to absorb, sometimes delaying noticeable effects until week 2
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