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The transcriptome and effector functions of Mdcs in neuroinflammatory disease is instructed by proinflammatory cytokines, including interferon- (IFN) and granulocyte macrophage colony-stimulating factor (GM-CSF), with subsets of moMACs and moDCs simultaneously expressing key urea cycle components including arginase 1 ( Arg1 ) and nitric oxide synthase 2 ( Nos2 ) 5,9

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