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Notably, AFB1 induced hepatocellular pyroptosis (434), and caused critical impairment of liver KCs (435)

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Future Research Directions and Unanswered Questions Despite 50+ years since Pickarts initial isolation work, significant mechanistic and clinical questions remain: Receptor identity: GHK-Cus gene regulatory effects are well-documented, but the specific cellular receptors mediating them remain incompletely characterized

Data saturation was judged to have been reached within the first 22 interviews, with a further 8 confirming it across the sample

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