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However, subcutaneous injection is the standard route for systemic and musculoskeletal effects, as it provides more reliable bioavailability and allows injection near the injury site
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Patients with pernicious anaemia, malabsorption disorders (such as Crohn's disease or coeliac disease), or following gastric surgery require regular B12 supplementation to prevent serious complications including megaloblastic anaemia and neurological damage
While most people can obtain sufficient B12 through their diet, some may face health problems like vitamin B12 deficiency due to inadequate absorption
A significant portion of the vitamin is lost before it ever reaches the bloodstream
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