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Longer-term use (6+ months) may create more durable improvements where enhanced dermal architecture supports ongoing collagen synthesis at rates intermediate between treatment peaks and pre-treatment baseline, potentially maintaining 40-60% of peak improvements indefinitely without continuous peptide application

doi: 10.3390/nu13062113 205 ODriscollM.Ribeiro Dos SantosG.WangL.CummingsD

This means consistent use over multiple cycles can continue to produce benefits without needing to increase the dose

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GHK-Cu Dosage Chart This GHK-Cu dosage chart explains a 100 mg vial prepared to a final volume of 3.0 mL for a concentration of 33.33 mg/mL