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For some groups, the numbers are even more concerning up to 90% of vegans and vegetarians may be deficient without proper supplementation

status in flux), and both are WADA-prohibited (class S2) for athletes

Studies show that NNMT inhibition by 5-amino-1-methylquinolinium significantly reduces nicotinamide metabolism, increases NAM accumulation, improves NAD+ synthesis efficiency by over 30%, and markedly increases mitochondrial ATP production and cellular energy metabolism

It complements 5-Amino-1MQ in recomposition or post-cycle protocols

Whether and how any of this translates into a meaningful outcome for a specific individual is exactly the kind of question that belongs in a clinical evaluation, not a generalized article