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While irritability is not officially recognized as a major side effect, it is still something that some people experience, and it is worth paying attention to

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In the latter half of the 20th century, Dow chemist Alexander Shulgin, famous for popularizing MDMA and a range of other potent psychedelic analogues, held gatherings at his home, sampling his latest creations with a group of like-minded fellow travelers

Of 544 screened papers, the reviewers identified 36 studies meeting inclusion criteria 35 preclinical and one human study