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It works by mimicking two gut hormones, GLP-1 and GIP, which help regulate blood sugar and appetite

1.0 to 1.7 mg semaglutide weekly

Retatrutide produces 82-86% reductions in liver fat at 48 weeks, with 89-93% of participants achieving less than 5% liver fat (the threshold for resolution of fatty liver disease)

This may promote fertility and pregnancy rates, per 2022 research in Obesity Medicine

Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial