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Whilst these medications effectively facilitate weight reduction, patients may notice skin changes including increased laxity or apparent thinning

It is deciding what to do, and crucially, what not to do

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Additional testing may be considered for people with a family history of premature heart disease, metabolic risk, abnormal cholesterol results, known cardiovascular disease, or uncertainty after standard testing: ApoB, Lp(a), and hs-CRP may help reveal particle burden, inherited risk, and inflammation that are not fully captured by LDL cholesterol alone

Tests include blood glutathione, markers of oxidative damage, amino acid precursors, and genomics tests for glutathione enzymes