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In 2021, Kishimoto et al., in a double-blind, placebo-controlled clinical trial, evaluated the anti-inflammatory effects of curcuRouge for 4 weeks on systemic inflammation in adults over 60 years of age in Japan [62]
doi:10.1002/ijc.2910620402
Additionally, GLP-1 receptor agonists (RAs) can reduce oxidative stress, benefiting the skin by protecting against free radicals that contribute to premature aging and acne-related inflammation
3.2.3.1 Oxidative stress regulation and mitochondrial protection HS mediates cardioprotection through dual antioxidant mechanisms: direct ROS scavenging and enhancement of the endogenous antioxidant system, thereby establishing a synergistic defense network for oxidative stress regulation and mitochondrial protection
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