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Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-kappaB and tumor progression

DSIP: DSIP is a nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) synthesized in the hypothalamus that modulates sleep architecture by promoting slow-wave (delta) sleep

Its well-characterized safety profile and natural presence in the body make it a particularly interesting candidate for cosmetic formulations and applications in cutaneous regenerative medicine

P., Rautama, E.-L

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