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In the absence of the cluster, such monothiol glutaredoxins can still be glutathionylated 26,27,29 and might (slowly) transfer the glutathione moiety to reduced cysteine residues as suggested for the AtGrxS15-dependent oxidation of reduced roGFP2 by GSSG
This association was particularly pronounced in RCTs lasting more than 104 weeks, where the odds ratio for thyroid cancer increased to 1.76
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Finally, preliminary ex-vivo data propose that the peptide complex might trigger Wnt/-catenin signaling cascades, pathways recognized for their role in hair follicle morphogenesis-although confirmation in human scalp tissue remains limited
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