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doi: 10.1172/jci36470, 20 BrodackiB.StaszewskiJ.ToczyowskaB.KozowskaE.DrelaN.ChalimoniukM.et al
It belongs to a novel class of agents known as triple agonists , meaning it simultaneously activates three distinct hormone receptors: GLP-1 (glucagon-like peptide-1) stimulates insulin secretion, reduces appetite, and slows gastric emptying [7] [8] GIP (glucose-dependent insulinotropic polypeptide) enhances insulin release and may improve fat metabolism Glucagon receptor increases energy expenditure and promotes fat breakdown (lipolysis)
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