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87 Although this rate was slightly lower than that observed in non-surgical controls (1.93 per 1 000 person-years), Cox regression analysis indicated no statistically significant difference in fracture risk (HR = 0.96, 95% CI: 0.831.11), suggesting that VSG may not substantially increase fracture incidence

Tirzepatide is an injectable medication that has gained significant attention for its dual benefits in people with type 2 diabetes: it helps regulate both blood sugar levels and appetite

However, as with other peptide systems discussed in this review, such variability often reflects limitations in measurement, context, or study design rather than the absence of biological relevance

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