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Over the past 50 years, more than 35% have been lost due to urbanization, agricultural intensification, and pollution
Moreover, iron-sulfur cluster proteins, essential cofactors for maintaining redox balance and iron levels, are produced as auxiliary enzymes in cuproptosis, with their levels significantly decreasing following cuproptosis initiation
61,103,270,282 Uric acid diminishes nitric oxide levels through several mechanisms, including the consumption of NO due to excessive reactive oxygen species production and direct inhibition of NO synthesis
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