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Generation of mice Col2-Cre mice 22 were mated with IR flox/flox mice, 21 and a breeding colony was maintained by mating IR flox/flox with Col2-Cre-IR flox/flox mice to generate CartIR / mice

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After 1-week acclimation period, the rats were divided into four groups: control ( n = 5), lenvatinib ( n = 5), lenvatinib + low-dose L-carnitine ( n = 5), and lenvatinib + high-dose L-carnitine ( n = 6)

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