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In addition, it may play a role in maintaining BBB integrity, regulating autophagy, and reducing the deposition of misfolded proteins

However, interpreting the health benefits of selenium against radiotherapy as the clinical validation of the radio-modulating activity of seleno-GPxs may be misleading, since selenium can manifest its beneficial effects through various mechanisms including but not limited to seleno-GPxs

Homocysteine and dementia: an international consensus statement