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Altitude/hypoxic exposures were static, but high-altitude dwellers may experience dynamic changes

Collectively, these findings demonstrate that gut microbiota dysbiosis contributes to the pathophysiology of schizophrenia through multifaceted immune-neuro-endocrine pathways, highlighting the MGB axis as a promising target for novel therapeutic strategies

FIGURE 5 Inhibition of the NF-B Pathway by GPX4 Activator We further demonstrated that GPX4 activator can modulate GPX4 mediated events

Subsequent handling and storage were conducted in a sterile environment to minimize microbial contamination during formulation and use

136, July 2015, pp