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119 CFTR is a 168 kDa protein and a member of the ATP-binding cassette transporter family, and its ATP-binding capacity allows it to facilitate the translocation of substrates across cellular membranes
Inhibition of glutaminolysis with the glutamine analogue 6-Diazo-5-oxo-L-norleucine (DON) reduces immune-induced and autoimmune Tfh cellular and humoral responses, selectively targeting pathogenic auto-reactive immune cells while preserving the ability of Tfh to generate protective responses against pathogens (55)
As a result, it makes you feel less hungry, slows down the emptying of your stomach and makes you feel 'fuller' for longer
Mannava S, Moparthy KC, Wheeler LJ, Natarajan V, Zucker SN, Fink EE et al