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The study began at the beginning of the dark phase with a single dose of each agonist or vehicle, combined with an IP glucose tolerance test (IPGTT)
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Lixisenatide is a daily GLP-1RA developed by Zealand Pharma, which prolongs its half-life through structure-inducing probe technology based on exendin-4/exenatide
These differences suggest that the choice of agent may depend on the specific ocular comorbidity and the patients baseline retinopathy status
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