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By confronting these barriers, DDS can transition from conceptual breakthroughs to clinically validated solutions, offering safer, more equitable, and globally accessible therapeutic strategies to reduce the socioeconomic burden of gout and hyperuricemia
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A., Hassanzadeh, M., Sharifi, N., & Shakeri, M
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Pharmacological contributors include thiazide diuretics (which inhibit renal urate secretion), cyclosporine (which reduces glomerular filtration), and pyrazinamide (which increases purine synthesis), all of which can precipitate secondary hyperuricemia (Zhang K
M., Al-Foheidi, M
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