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Tapering also gives you time to reinforce behavioral strategiesmeal planning, portion awareness, and physical activity patternsthat become your primary weight maintenance tools once medication ends
During, M
Its not necessarily the GLP, the medication itself, its weight loss
hypoglycemia risk if on insulin) eGFR below 30 (tirzepatide exclusion in SURMOUNT-5) Recent cardiac event or NYHA Class IV heart failure Active suicidal ideation (trials excluded PHQ-9 scores of 15 or above) If your tirzepatide vs semaglutide question is pure weight loss without comorbidities, tirzepatide wins on the numbers
However, individuals with a history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, pancreatitis, or severe gastrointestinal disorders should discuss alternative therapies with their provider
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