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GI events were the most common adverse effects, with the vast majority being mild to moderate in severity

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Moreover, within the biological process category, cellular process, regulation of biological process, and biological regulation were identified as key processes

Long-term DHA deficiency may increase the incidence of mood and behavior disorders in children [32]

Additionally, the CheckMate 18 phase III clinical trial, focusing on individuals with inoperable or metastatic melanoma, revealed a 43.6% objective response rate (ORR) in PD-L1-positive patients treated with nivolumab, compared to 9.1% in those receiving chemotherapy [116]