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Clinically, observational data suggest a 19% lower glaucoma incidence in GLP-1RA-treated diabetic patients than those on other antidiabetic regimens (Figure 1, this review comprehensively analyzes the mechanistic basis of GLP-1RAs in ocular diseases, synthesizes emerging clinical and preclinical evidence, and underscores their potential to redefine therapeutic strategies for vision-threatening disorders through multi-targeted disease modification

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