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A Biopharmaceutical Mechanistic Perspective
The role of oxidative stress and antioxidants in male fertility
In addition to the lower incidence of nonfatal stroke in clinical trials [22, 40, 57], treatment with liraglutide or semaglutide (sc or oral) decreased the risk of dementia by 53% compared to the risk associated with placebo (HR 0.47, 95% CI 0.250.86) according to a pooled post hoc analysis of the LEADER, SUSTAIN 6 and PIONEER 6 trials, including 15,820 patients with T2DM [65]
Participants were divided into those receiving concurrent hormone therapy and those who were not, with groups carefully matched by age, BMI, and clinical history to reduce the most obvious confounding variables
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