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PubMed laboratory research record [PMID: 9178805] PubMed record related to this compound for laboratory literature review

The full Phase 3 clinical-trial results should provide a clearer picture soon, but one noteworthy finding so far is dysesthesia, or odd sensations in the skin, such as burning and pain, that suggest unrest in the nervous system

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Glucagon receptor activation increases hepatic glucose output and, at doses balanced against GLP-1R-mediated insulin secretion, raises basal metabolic rate by 10 to 20% in preclinical models without net hyperglycemia