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Seiwerth S, Brcic L, Vuletic LB, Kolenc D, Aralica G, Misic M, et al
Among them, the amino acid NH 3+ stretching vibration at 2,938 cm 1 , the sulfur hydrogen S-H stretching vibration at 2,524 cm 1 , the carboxylate COO stretching vibration at 1,712 cm 1 , the carbonyl C=O bond stretching (amide I) vibration at 1,660 cm 1 , and the CN Hbond bending vibration (secondary amide amide II) at 1,395 cm 1 , the carboxylic acid root COO symmetric stretching vibration at 1,395 cm 1 , and the CN stretching vibration caused by CN stretching vibration at 1,248 cm 1
The resulting peptide has a nearly identical 3D spatial arrangement of functional groups as the originalmaintaining target binding affinitybut is unrecognizable to proteases that cleave L-amino acid peptide bonds
Its worth noting that the risk of side effects may vary from person to person, and some individuals may not experience any adverse reactions
Systemic effect across multiple sites
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