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4e, f, both G/D-CuP and D-CuP exhibited a significant reduction in the expression levels of pro-inflammatory cytokines

Despite proven efficacy, both treatments are limited by inconsistent responses, the need for ongoing use, recurrence after discontinuation, and side effects such as scalp irritation and sexual or hormonal issues [6, 7]

K., Lierman, J

Once secreted, GLP-1 has a very short half-life of approximately 1-2 minutes in the circulation, as it is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4)

For most people, it works best as part of a comprehensive fatloss strategy, not a replacement for one.