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Given that an increase, but not a decrease, in the Kyn/Trp ratio is expected to be associated with inflammation, and that we observe a one-directional trend towards increased values among the asymptomatic V30M carriers compared to controls (Table 2

Anti-inflammatory and antioxidant therapies, including N-acetylcysteine, vitamin C, coenzyme Q10, alpha-lipoic acid, and green tea extract, were primarily evaluated for their effects on oxidative stress, inflammation, endothelial function, and cardiovascular markers

While copper peptides are unlikely to reverse graying that has already occurred, maintaining adequate copper levels in the scalp may help support natural pigment production for longer

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The transition from daily injections to weekly dosage and, finally, to oral formulations has considerably enhanced the treatment environment