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During the lytic phase of HSV-1, either in neurons or epithelial cells the virus expresses its genes in a cascade-dependent manner, with three major waves of transcription: first, the expression of immediate early genes (IE or alpha genes), followed by the expression of early genes (E or beta genes) and lastly, late genes (L or gamma genes)

Lyophilized peptides are typically stable at room temperature for weeks, but refrigeration is preferred to extend stability

The formation of diselenide bridges in proteins by incorporation of selenocysteine residues: biosynthesis and characterization of (Se) 2-thioredoxin

Every minute it spends at room temperature is a minute you're giving potential microbes a warmer, more inviting environment to grow

Preclinical results are consistently positive in tissue repair contexts, but animal data cannot confirm human efficacy