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First, when you take a pill, it has to be digested and metabolized through the liver or kidney through what is called the first-pass effect

For example, concurrent use of chloramphenicol (an antibiotic) may attenuate the hematologic response to vitamin B therapy

Generic oral B12 is inexpensive (often just a few dollars/month)

Vitamin B-12 deficiency is not super common in the U.S