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Expert Opin Drug Metab Toxicol 10:10051017
The primary role of the renal and urinary system is to aid detoxification by filtering and removing waste products, drugs, and toxins
Upon further examination, upregulated genes were found to predominantly influence metabolic processes, particularly in organic substance metabolic processes and cellular nitrogen compound metabolic processes
This has made glutathione and its precursors an active research area for reducing chemotherapy-related kidney injury, under medical supervision
Enzymatic glutathionylation reactions are tightly controlled and highly specific and are considered a major post-translational modification that occurs in response to fluctuations in local redox environments
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