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Furthermore, several terms upregulated in old indicate active metabolic detoxification processes (for example, alcohol metabolic process and cellular aldehyde metabolic process), as well as oxidative stress defense (for example, glutathione metabolic process) and remodeling of the extracellular matrix (for example, uronic acid metabolic process, extracellular matrix organization and biological adhesion)

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RAMPs change calcitonin receptor pharmacology from calcitonin-preferring to amylin-preferring by affecting receptor specificity and affinity