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Smaller, frequent meals work better than skipping food when appetite is suppressed

In Study 2 (NCT00553787), patients with overweight or obesity were randomized to receive 1 year of treatment with placebo (N=994), phentermine and topiramate extended-release 7.5 mg/46 mg (N=498), or phentermine and topiramate extended-release 15 mg/92 mg (N=995) in a 2:1:2 ratio

Immune System Coordination Immune cells, such as T-cells and Natural Killer (NK) cells, require glutathione to function and multiply correctly

It may be a better fit for patients seeking more robust weight loss potential, patients with stronger appetite signals, or patients who did not get their desired response from semaglutide

Nicu C, O'Sullivan JDB, Ramos R, Timperi L, Lai T, Farjo N