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further research is needed to enable broader applicability in the case of breast cancer (120)

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also discussed the biological plausibility of GLP-1 RAs influencing thyroid cells, citing preclinical evidence of GLP-1 receptors in thyroid tissue

479 Another cascade linking astrocytes to the pathophysiology of Down syndrome is an increased production of hydrogen sulphide, which is catalysed by cystathionine--synthase expressed, more or less exclusively, in astrocytes, and upregulated in a rat model of the disease