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37 RCTs Meta-Analysis (2020) Weight loss: -1.13 kg BMI: -0.36 points Fat mass: -1.16 kg Waist circumference: -1.24 cm Umbrella Meta-Analysis (2025) Confirms: statistically significant weight loss , especially combined with exercise
One of the studies, SUSTAIN-6, was a 2-year FDA-mandated cardiovascular-outcomes trial involving 3297 patients
United Laboratories retained Chinese rights
For this analysis, the population with obesity is defined as those patients with one or more obesity-related diagnostic claims, including BMI-related codes
This article explains which products pose the greatest risk, what NHS and MHRA guidance advises, and how to manage your weight safely alongside thyroid medication
