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Common interactions to discuss with your provider include: Metformin and semaglutide or metformin and tirzepatide : often combined for diabetes management alongside HRT

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For others, the changes in gut hormones may influence the production of neurotransmitters like serotonin, which plays a major role in mood stability

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These processes, in turn, influence the function of hepatocytes, hepatic stellate cells, and macrophages, thereby contributing to the development of hepatic steatosis and fibrosis