The gut microbiome in psoriasis and psoriatic arthritis
Sequential initiationadding one agent, allowing 48 weeks for tolerance to develop, then introducing the secondmay improve tolerability, particularly regarding gastrointestinal side effects from GLP-1 receptor agonists
To view or add a comment, sign in What is the normal range for platelet count? Platelets, or thrombocytes, are anucleate cytoplasmic fragments derived from megakaryocytes in the bone marrow
Variants in GIPR (the GIP receptor itself, including rs1800437), FTO (appetite regulation), MC4R (satiety signaling), and TCF7L2 (insulin response) are associated with different response patterns to tirzepatide and semaglutide
Gradual introduction of allulose into the diet may help minimise gastrointestinal discomfort as the gut microbiome adapts