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A frequently cited study reported changes in telomerase activity and lifespan-related outcomes in mice: Biogerontology study on Epitalon

The GLP-1 RAs were originally developed for the treatment of type 2 diabetes mellitus (T2DM), but they soon showed promising effects in weight reduction [1, 2]

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Together they attack obesity from multiple angles simultaneously, explaining the superior results compared to single or dual pathway approaches