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Dosage and Administration of Saxagliptin The recommended dosage of saxagliptin for the management of type 2 diabetes mellitus is 2.5 mg or 5 mg administered orally once daily, with or without food

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Targeting MQC to activate PINK1-Parkin-mediated mitophagy upregulates GPX4/SLC7A11, reducing lipid peroxides and iron accumulation, which inhibits ferroptosis and alleviates cartilage damage

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The comparison in both cases was patients on an SGLT2 inhibitor, a different class of diabetes medication used as an active comparator

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