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71 In addition, extra-mitochondrial localization of branched-chain -keto acid dehydrogenase (BCKDH), a rate-limiting enzyme in BCAAs metabolism, has been reported in type 2 diabetic rat model (OLETF)

DSIPs side effect profile appears mild compared to pharmaceutical sleep aids, with most reported effects relating to dose or timing issues rather than inherent toxicity

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What it looks like in practice An injectable form of DSIP typically involves either subcutaneous (under the skin) or sometimes intravenous (into the vein) administration in research settings