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Yet, its results may be more subtle and gradual compared to Aqualyx

Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma

One hour later, rats were anesthetized with ketamine (90 mg/kg), xylazine (2.8 mg/kg), and acepromazine (0.72 mg/kg) and transcardially perfused with 0.1 M phosphate-buffered saline (PBS) followed by 4% paraformaldehyde (PFA) in PBS