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For regular drinkers (3+ drinks per week), daily NAC (600mg) or alpha-lipoic acid (300mg) supports baseline glutathione synthesis without suppressing endogenous production, and both have been studied in chronic alcohol use populations with positive hepatoprotective outcomes

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PMCID: PMC7447324

Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia