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The GM plays a primary role in the progression of OP by producing metabolites, regulating intestinal mucosal permeability, and modifying submucosal immunity
Reduced Muscle and Bone Density: Menopause can increase muscle loss while decreasing bone density as estrogen levels drop
This is risky because supplements are not regulated with the same rigor as prescription drugs, making it difficult to know exactly how much active compound you are receiving
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Under physiological conditions, ROS are generated in the heart mainly from the mitochondrial electron transport chain, nitric oxide synthases (NOS), NADPH oxidases (NOX), and xanthine oxidase (XO) in small quantities [7, 8]
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