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Data Animal Data In pregnant rats given twice weekly subcutaneous doses of 0.02, 0.1, and 0.5 mg/kg tirzepatide (0.03-, 0.07-, and 0.5-fold the maximum recommended human dose (MRHD) of 15 mg once weekly based on AUC) during organogenesis, increased incidences of external, visceral, and skeletal malformations, increased incidences of visceral and skeletal developmental variations, and decreased fetal weights coincided with pharmacologically-mediated reductions in maternal body weights and food consumption at 0.5 mg/kg

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Efficacy of exenatide administered twice daily in body mass index reduction in patients with type 2 diabetes mellitus

You may feel fuller after smaller meals and experience fewer cravings within the first week

Small, frequent meals can also help stabilize your blood sugar levels, preventing energy crashes