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Its cell-penetrating properties allow it to enter cells without transfection or vector delivery, where it directly engages the p53 TAD2 domain to disrupt the FOXO4-p53 complex

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Miller AA, Kurschel E, Osieka R, Schmidt CG

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EClinicalMedicine 3(72):102624 Jensen SBK, Srensen V, Sandsdal RM, Lehmann EW, Lundgren JR, Juhl CR et al (2024) Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment: A Secondary Analysis of a Randomized Clinical Trial