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It might lose a small percentage of potency over years, but the molecule itself remains largely intact
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Phase 2a included patients with suspected NASH (30% of cohort) who achieved similar up to 82.4% liver fat reduction and enzyme normalization
The typical treatment protocol starts with a 2.5 mg dose, gradually increasing to 15 mg to minimize gastrointestinal side effects
Factors like kidney function, tolerance, and treatment goals matter when determining whether this combination is appropriate
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