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According to FDA prescribing information for semaglutide and liraglutide, hypersensitivity reactions are rare but possible
Therefore, more efforts should be taken to develop metal-based nanoplatforms with excellent targeting specificity to cancer cells based on the characteristics of TME and GSH exhaustion mechanisms
Triple-Agonist Mechanism of Action GLP-1 Pathway (Glucagon-Like Peptide-1) Activates receptors in the hypothalamus to reduce appetite, stimulates insulin secretion from pancreatic beta cells, and slows gastric emptying
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While our current study provides significant insights into the neuroprotective role of Irisin through its modulation of microglia-induced neurotoxicity, it is important to acknowledge that exploring the involvement of astrocytes and the broader neuroimmune response remains beyond the scope of this manuscript
