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ClinicalTrials.gov has assigned the study number NCT03806478 to the APH-1105 study, which is a Phase 2 clinical investigation that was launched in 2019

CL Answer ConsumerLabs Review of ION* Gut Support ConsumerLab's Review of ION Gut Support (formerly Restore), the liquid humic extract supplement derived from soil

Titration is key: Gradual dose escalation maximizes tolerability

However, very few studies used doses lower than 20 g

Amylin acts on the area postrema (brainstem) and lateral parabrachial nucleus to reduce hedonic eatingthe reward-driven 'want to eat' circuits that operate independently of energy balance