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Prevention of Erastin-Induced Ferroptosis by GPX4 Activator in HT-1080 Cells HT-1080 cells were cultured in DMEM containing 10% FBS, 1% supplemented non-essential amino acids and 1% Pen-Strep mixture (all from Gibco) and maintained in a humidified atmosphere with 5% CO 2 at 37C
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In a subanalysis of SURPASS-3, tirzepatide 10 and 15 mg resulted also in a relative reduction in liver fat content by 4047% compared to 11% with insulin glargine at 52 weeks [44]
These modifications result in a compound approximately 1,000 times more potent than natural -MSH at activating melanocortin receptors
